Nanotechnology, the new science of extreme miniaturization, is a rapidly growing field in engineering. On this size scale, it is extremely difficult and expensive to fabricate analogs of macroscale engineering, such as grippers. Drawing inspiration from biological fabrication in nature, engineers are seeking to self-assemble structures from the bottom up. This manufacturing paradigm has been largely unexplored in human engineering since the process is generally perceived to be indeterminable and uncontrollable. The Gracias Lab at Johns Hopkins has developed a relatively easy, precise, and cost-effective process by which the 2D templates of semi-tethered “faces” can self-assemble into controlled 3D structures by utilizing the natural phenomena of surface tension. This video highlights the development, manufacturing process, and proposed functions (cell encapsulation devices and controlled drug delivery carriers) of our self-assembling nanoliter containers.
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Nanomedicine – The Latest Buzz In The Field Of Medicines!

Technology and medical science has evolved at a greater pace as compared to the evolution of human beings. Every now and then, there are developments. One of the latest in the medical science is the Nanomedicine. Man ever since has understood the nuances of life have been worried about the day when he would have to face death. He understands that every thing that is born would die, but doesn’t want to acknowledge this fact. Man is trying to explore every possibility to sustain the life. He wants to defeat death and wants some kind of remedy, which would help humans being youthful and alive forever.

Nanomedicine is the output of the nanotechnology. This could be understood as a very tiny step towards human desire to live. There are so many diseases and there are cures as well. However, no one cure could be 100% and side effects should be expected. With the use of Nanomedicine, the side effects of the medicines and therapy conducted for a disease could be reduced and success rate of the effectiveness of the same could be increased. This simply means that Nanomedicine is a booster that would help make the tools of medical science even stronger than before.

The principle on which this medicine works is, this technique would aim at utilizing nanoparticles, sensors after a detailed diagnosis and the MEMS (micro-electro mechanical system) and then monitor & observe the vivo bio chemical activities.

The advantages of Nanomedicine are listed below –

By just modifying the genetic material diseases as deadly as caner could be taken care off. Disease elimination will become normal. With this, before the symptoms are on the surface the disease could be diagnosed. It administers drugs. Uses tools that can gauge the effectiveness of the treatment

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Aarkstore Enterprise -Advances in nanotechnology – Innovations in Oral Solid Drug Delivery: controlled formulations & peptide delivery-Aarkstore E

Innovations in Oral Solid Drug Delivery: Advances in nanotechnology, controlled formulations & peptide delivery

 
Table of Contents : 

Innovations in oral solid drug delivery
Executive summary 18
Market overview, dynamics and outlook 18
Advances in nanotechnology 19
Innovations in transitioning injectables to oral delivery 20
Advances in delayed & controlled release delivery 21
Advances in oral prodrug delivery 22
Advances in taste masking technologies 23
Innovative companies 24
Chapter 1 Market overview, dynamics and outlook 28
Summary 28
Market overview 29
Market dynamics 31
Key indications 33
Key trends 38
Nanomedicine 38
Transitioning from injectables 39
Prodrugs 40
Chrono release 41
ODT 41
OSF 42
Funding issues 42
Poor patient compliance 42
Injections 42
Poor absorbption 42
Pediatric 43
Geriatric 43
Solubility and variable absorption 43
Reduction of side effect profiles 44
Non-invasive protein delivery 45
Transition from injectables to preferred route of oral drug delivery 45
Directed delivery and delayed delivery to reduce side effect potential 46
Formulation technologies for poorly soluble compounds 46
Taste masking for pediatric and geriatric formulations 47
Competitive landscape 48
Conclusions and key findings 50
Chapter 2 Advances in nanotechnology 56
Summary 56
Introduction 57
Nanotechnology platforms with application for oral drug delivery 59
Self-Emulsifying Controlled Release Tablet system (SECRET) 59
Technology 59
Application 59
Biotransport nanomedicine technology 60
Technology 60
Application 60
Nanobodies 61
Technology 61
Application 61
NanoDel nanoparticles 62
Technology 62
Application 62
P-gpMask 63
Technology 63
Application 64
NanoDRY and NanoCOAT 64
Technology 64
Application 64
Solumer 67
Technology 67
Application 67
Nanocells 69
Technology 69
Application 70
Polymeric Nano-Delivery System (PNDS) 70
Technology 70
Application 71
FluidCrystal NP Oral nanoparticles 71
Technology 71
Application 72
CaP Technology and BioOral 72
Technology 72
Application 73
Nab Technology and Protospheres 73
Technology 73
Application 73
NanoCrystal Technology 74
Technology 74
Application 74
Bioral 75
Technology 75
Application 75
Squalenoyl nanoparticles 76
NanoMega 76
NOD Pharmaceutical 76
Chapter 3 Innovations in transitioning injectables to oral delivery 80
Summary 80
Introduction 81
Drivers 81
Patient acceptability & compliance 81
Cost savings 81
Restraints 82
Advances in injectable delivery 82
Challenges of oral drug delivery 83

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Nanobiotechnology,a Quantum Scientific Approach in 21st Century

Nanobiotechnology,a quantum scientific approach in 21st century

Imagination is the key in human life and is the main force behind every development of human lifestyle. Considering the impact of science and technology on the human race, it is natural to think ‘Nothing is Impossible’.

Biotechnology is the application of biological research techniques to develop immense products for mankind. Whereas, nanobiotechnology is the application of nano-scaled tools to biological systems and the other is the use of biological systems as templates in the development of novel nano-scaled products. Simply a nano-biotechnology is the complex of nanotechnology and biotechnology. Each of these technologies has a tremendous impact by itself and therefore when they complement each other it results in efficacious fourth dimensional solutions.

Nanotechnology used in biotechnology usually called nanobiotechnology is definitely a life-saving innovation that has come as a boon to mankind. It involves the creation and use of materials and devices at the level of molecules and atoms for the development of Nanomedicine, Nanosensors, Nanofluidics and Nanofabrics. It is a valuable contribution of the profound research by scientists and engineers to create new systems with novel functionalities.

Nanomedicine is one of an offshoot of nanotechnology, refers to highly specific medical intervention at the molecular level for curing disease or repairing damaged tissues, such as bone, muscle, or nerve. The existing means of intake of drugs orally or through injections are becoming moderately effective but can be extremely painful due to the non-availability of accurate diagnosis. The concept of nanomedicine involves the newer methods to deliver drugs at the right place, time, and amounts in the body. Scientists and engineers have developed new systems where the human-body parameters are monitored using a techno-monitor (semiconductor chip) that is placed inside a human body. These chips are the “nano” machines which are compatible with living tissues and can be safely operated inside the body.

For example: When a patient is being treated for diabetes, the semiconductor chip monitors the blood-sugar levels and passes on the information to the device outside of the body. The external device, in turn, instructs the semiconductor chip that acts as the drug delivery system, to release the right amounts of insulin into the blood, thus causing less or no side effects to the patient.

The approach of nanomedicine is versatile and will completely revolutionize the diverse branches of medicine in near future. It involves the application of nanoparticles for cancer imaging and therapy, drug delivery for prostate cancer and nanowire devices for virus detection and cancer screening too. Thus, nanomedicine is simply the preservation and improvement of human health

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